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1

Hydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice

Suzuki, Yohei, Sato, Tadashi, Sugimoto, Masataka, Baskoro, Hario, Karasutani, Keiko, Mitsui, Aki, Nurwidya, Fariz, Arano, Naoko, Kodama, Yuzo, Hirano, Shin-ichi, Ishigami, Akihito, Seyama, Kuniaki, Ta

Journal:

Biochemical and Biophysical Research Communications

Year:

2017

Language:

english

File:

PDF, 25.89 MB

english, 2017

2

Quantification of elastin cross-linking amino acids, desmosine and isodesmosine, in hydrolysates of rat lung by ion-pair liquid chromatography–mass spectrometry

Naoko Kaga, Sanae Soma, Tsutomu Fujimura, Kuniaki Seyama, Yoshinosuke Fukuchi, Kimie Murayama

Journal:

Analytical Biochemistry

Year:

2003

Language:

english

File:

PDF, 259 KB

english, 2003

3

Breakthrough lung Scedosporium prolificans infection with multiple cavity lesions in a patient receiving voriconazole for probable invasive aspergillosis associated with monoclonal gammopathy of undetermined significance (MGUS)

Ohashi, Rina, Kato, Motoyasu, Katsura, Yoko, Takekawa, Hidenori, Hoshika, Yoshito, Sugawara, Tomonori, Yoshimi, Kaku, Togo, Shinsaku, Nagaoka, Tetsutaro, Seyama, Kuniaki, Takahashi, Kazuhisa, Tsuchiya

Journal:

Nippon Ishinkin Gakkai Zasshi

Year:

2011

Language:

english

File:

PDF, 587 KB

english, 2011

4

Mineralization of alpha-1-antitrypsin inclusion bodies in Mmalton alpha-1-antitrypsin deficiency

Callea, Francesco, Giovannoni, Isabella, Francalanci, Paola, Boldrini, Renata, Faa, Gavino, Medicina, Daniela, Nobili, Valerio, Desmet, Valeer J., Ishak, Kamal, Seyama, Kuniaki, Bellacchio, Emanuele

Journal:

Orphanet Journal of Rare Diseases

Year:

2018

Language:

english

File:

PDF, 1.44 MB

english, 2018

5

A total pleural covering of absorbable cellulose mesh prevents pneumothorax recurrence in patients with Birt-Hogg-Dubé syndrome

Mizobuchi, Teruaki, Kurihara, Masatoshi, Ebana, Hiroki, Yamanaka, Sumitaka, Kataoka, Hideyuki, Okamoto, Shouichi, Kobayashi, Etsuko, Kumasaka, Toshio, Seyama, Kuniaki

Journal:

Orphanet Journal of Rare Diseases

Year:

2018

Language:

english

File:

PDF, 1.86 MB

english, 2018

6

Transbronchial lung biopsy for the diagnosis of lymphangioleiomyomatosis: the severity of cystic lung destruction assessed by the modified Goddard scoring system as a predictor for establishing the diagnosis

Okamoto, Shouichi, Suzuki, Kazuhiro, Hayashi, Takuo, Muraki, Keiko, Nagaoka, Tetsutaro, Nishino, Koichi, Sekimoto, Yasuhito, Sasaki, Shinichi, Takahashi, Kazuhisa, Seyama, Kuniaki

Journal:

Orphanet Journal of Rare Diseases

Year:

2020

File:

PDF, 617 KB

2020

7

Analysis of all exons oftsc1 andtsc2 genes for germline mutations in Japanese patients with tuberous sclerosis: Report of 10 mutations

Yamashita, Yokihiko, Ono, Jiro, Okada, Shintaro, Wataya-Kaneda, Mari, Yoshikawa, Kunihiko, Nishizawa, Masae, Hirayama, Youko, Kobayashi, Etuko, Seyama, Kuniaki, Hino, Okio

Journal:

American Journal of Medical Genetics

Year:

2000

Language:

english

File:

PDF, 61 KB

english, 2000

8

Identification of intragenic deletions and duplication in the FLCN gene in Birt-Hogg-Dubé syndrome

Jihane N. Benhammou, Cathy D. Vocke, Avni Santani, Laura S. Schmidt, Masaya Baba, Kuniaki Seyama, Xiaolin Wu, Susana Korolevich, Katherine L. Nathanson, Catherine A. Stolle, W. Marston Linehan

Journal:

Genes, Chromosomes and Cancer

Year:

2011

Language:

english

File:

PDF, 408 KB

english, 2011

9

Differential detection of PAS-positive inclusions formed by the Z, Siiyama, and Mmalton variants of α1-antitrypsin

Sabina Janciauskiene, Sten Eriksson, Francesco Callea, Meera Mallya, Aiwu Zhou, Kuniaki Seyama, Satoru Hata, David A. Lomas

Journal:

Year:

2004

Language:

english

File:

PDF, 591 KB

english, 2004

10

Summary of the afternoon discussion session

Yoshinosuke Fukuchi, Norbert Berend, Kuniaki Seyama

Journal:

Year:

2001

Language:

english

File:

PDF, 37 KB

english, 2001

11

State of alpha1-antitrypsin deficiency in Japan

Journal:

Year:

2001

Language:

english

File:

PDF, 221 KB

english, 2001

12

Longitudinal follow-up study of 11 patients with pulmonary lymphangioleiomyomatosis: Diverse clinical courses of LAM allow some patients to be treated without anti-hormone therapy

KUNIAKI SEYAMA, SHIRO KIRA, HIDEKI TAKAHASHI, MASAHIRO OHNISHI, YUZO KODAMA, TAKASHI DAMBARA, JUNE KOBAYASHI, SATOSHI KITAMURA, YOSHINOSUKE FUKUCHI

Journal:

Year:

2001

Language:

english

File:

PDF, 577 KB

english, 2001

13

Classification of mutations in the human CD40 ligand, gp39, that are associated with X-linked hyper IgM syndrome

Jürgen Bajorath, Kuniaki Seyama, Shigeaki Nonoyama, Hans D. Ochs, Alejandro Aruffo

Journal:

Protein Science

Year:

1996

Language:

english

File:

PDF, 2.17 MB

english, 1996

14

Cells derived from tuberous sclerosis show a prolonged S phase of the cell cycle and increased apoptosis

M. Wataya-Kaneda, Yasufumi Kaneda, Okio Hino, Hiroyuki Adachi, Youko Hirayama, Kuniaki Seyama, Teruhiko Satou, Kunihiko Yoshikawa

Journal:

Archives of Dermatological Research

Year:

2001

Language:

english

File:

PDF, 299 KB

english, 2001

15

Mutations of the CD40 ligand gene in 13 Japanese patients with X-linked hyper-IgM syndrome

Shigeaki Nonoyama, Mitsunobu Shimadzu, Hano Toru, Kuniaki Seyama, Hiroyuki Nunoi, Michael Neubauer, Jun-ichi Yata, Hans D. Ochs

Journal:

Year:

1997

Language:

english

File:

PDF, 65 KB

english, 1997

16

Progressive interstitial pneumonia associated with myelodysplastic syndrome: Implication of superoxide hyperproduction by neutrophils

Yumi TAMAKI, Kuniaki SEYAMA, Hideki TAKAHASHI, Takao HIRANO, Toshimasa UEKUSA, Takashi DAMBARA, Shiro KIRA, Yoshinosuke FUKUCHI, Shigeru TOMINAGA

Journal:

Year:

1997

Language:

english

File:

PDF, 644 KB

english, 1997

17

The epidemiology of lymphangioleiomyomatosis in Japan: A nationwide cross-sectional study of presenting features and prognostic factors

Mie HAYASHIDA, Kuniaki SEYAMA, Yoshikazu INOUE, Keisaku FUJIMOTO, Keishi KUBO, The Respiratory Failure Research Group of the Japanese Ministry of Health, Labor, , Welfare

Journal:

Year:

2007

Language:

english

File:

PDF, 157 KB

english, 2007

18

Survey of implementation of the Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines in nine Asian countries

Yuzo Kodama, Kuniaki Seyama, Kaku Yoshimi, June Ueki, Hideichi Oka, Yoshinobu Ikari, Yoshinosuke Fukuchi

Journal:

Geriatrics & Gerontology International

Year:

2007

Language:

english

File:

PDF, 322 KB

english, 2007

19

Senescence Marker Protein-30 Knockout Mouse as an Aging Model

NAOKI MARUYAMA, AKIHITO ISHIGAMI, MASASHI KURAMOTO, SETSUKO HANDA, SACHIHO KUBO, TOSHIYUKI IMASAWA, KUNIAKI SEYAMA, TATSUO SHIMOSAWA, YASUSHI KASAHARA

Journal:

Annals of the New York Academy of Sciences

Year:

2004

File:

PDF, 2.02 MB

2004

20

Amylase mRNA transcripts in normal tissues and neoplasms: the implication of different expressions of amylase isogenes

Kuniaki Seyama, Toshihiro Nukiwa, Kazuhisa Takahashi, Hideki Takahashi, Shiro Kira

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

1994

Language:

english

File:

PDF, 1.10 MB

english, 1994

21

Phospholipid requirement of alkylglycerol monooxygenase from rat liver microsomes

Teruo Ishibashi, Kuniaki Seyama

Journal:

Year:

1986

Language:

english

File:

PDF, 382 KB

english, 1986

22

Biochemical characterization of acetyl-CoA:1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase in rat spleen microsomes

Kuniaki Seyama, Teruo Ishibashi

Journal:

Year:

1987

Language:

english

File:

PDF, 538 KB

english, 1987

23

A quantitatively-modeled homozygosity mapping algorithm, qHomozygosityMapping, utilizing whole genome single nucleotide polymorphism genotyping data

Huqun*, Shun-ichiro Fukuyama, Hiroyuki Morino, Hiroshi Miyazawa, Tomoaki Tanaka, Tomoko Suzuki, Masakazu Kohda, Hideshi Kawakami, Yasushi Okazaki, Kuniaki Seyama, Koichi Hagiwara

Journal:

BMC Bioinformatics

Year:

2010

Language:

english

File:

PDF, 670 KB

english, 2010

24

Senescence marker protein-30 knockout mouse as a novel murine model of senile lung

Takanori Mori, Akihito Ishigami, Kuniaki Seyama, Reiko Onai, Sachiho Kubo, Kazue Shimizu, Naoki Maruyama, Yoshinosuke Fukuchi

Journal:

Pathology International

Year:

2004

Language:

english

File:

PDF, 235 KB

english, 2004

25

Osteopontin expression in pulmonary tumor thrombotic microangiopathy caused by gastric carcinoma

Fumiyuki Takahashi, Toshio Kumasaka, Tetsutaro Nagaoka, Midori Wakiya, Hiroaki Fujii, Kazue Shimizu, Koji Uchida, Yoshiteru Morio, Kuniaki Seyama, Okio Hino, Kazuhisa Takahashi, Yoshinosuke Fukuchi

Journal:

Pathology International

Year:

2009

Language:

english

File:

PDF, 427 KB

english, 2009

26

Factors influencing weaning from mechanical ventilation in elderly patients with severe pneumonia

Mitsuhiro Fujii, Shin-ichiro Iwakami, Haruhi Takagi, Yukinari Itoigawa, Masako Ichikawa, Naoko Iwakami, Toshiji Ishiwata, Kuniaki Seyama, Kazuhisa Takahashi

Journal:

Geriatrics & Gerontology International

Year:

2012

Language:

english

File:

PDF, 153 KB

english, 2012

27

Immunologic Reconstitution Following Bone Marrow Transplantation for X-Linked Hyper IgM Syndrome

John E. Duplantier, Kuniaki Seyama, Noorbibi K. Day, Remi Hitchcock, Robert P. Nelson Jr., Hans D. Ochs, Soichi Haraguchi, Martin R. Klemperer, Robert A. Good

Journal:

Clinical Immunology

Year:

2001

Language:

english

File:

PDF, 221 KB

english, 2001

28

Metabolism of platelet-activating factor in primary cultured adult rat hepatocytes by a new pathway involving phospholipase C and alkyl monooxygenase

Okayasu Takako, Hoshii Koichi, Seyama Kuniaki, Ishibashi Teruo, Imai Yoh

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1986

Language:

english

File:

PDF, 755 KB

english, 1986

29

Characteristics of pulmonary cysts in Birt–Hogg–Dubé syndrome: Thin-section CT findings of the chest in 12 patients

Kazunori Tobino, Yoko Gunji, Masatoshi Kurihara, Makiko Kunogi, Kengo Koike, Noriyuki Tomiyama, Takeshi Johkoh, Yuzo Kodama, Shin-ichiro Iwakami, Mika Kikkawa, Kazuhisa Takahashi, Kuniaki Seyama

Journal:

European Journal of Radiology

Year:

2011

Language:

english

File:

PDF, 766 KB

english, 2011

30

Differentiation between Birt–Hogg–Dubé syndrome and lymphangioleiomyomatosis: Quantitative analysis of pulmonary cysts on computed tomography of the chest in 66 females

Kazunori Tobino, Toyohiro Hirai, Takeshi Johkoh, Masatoshi Kurihara, Kiminori Fujimoto, Noriyuki Tomiyama, Michiaki Mishima, Kazuhisa Takahashi, Kuniaki Seyama

Journal:

European Journal of Radiology

Year:

2012

Language:

english

File:

PDF, 657 KB

english, 2012

31

Sirolimus Amelioration of Clinical Symptoms of Recurrent Lymphangioleiomyomatosis After Living-donor Lobar Lung Transplantation

Ryujiro Sugimoto, Atsunori Nakao, Masaomi Yamane, Shinichi Toyooka, Megumi Okazaki, Motoi Aoe, Kuniaki Seyama, Hiroshi Date, Takahiro Oto, Yoshifumi Sano

Journal:

The Journal of Heart and Lung Transplantation

Year:

2008

Language:

english

File:

PDF, 1.01 MB

english, 2008

32

Matrix metalloproteinases in blood from patients with LAM

Nao Odajima, Tomoko Betsuyaku, Yasuyuki Nasuhara, Hiromasa Inoue, Kuniaki Seyama, Masaharu Nishimura

Journal:

Respiratory Medicine

Year:

2009

Language:

english

File:

PDF, 207 KB

english, 2009

33

Additive effects of transdermal tulobuterol to inhaled tiotropium in patients with COPD

Masakazu Ichinose, Kuniaki Seyama, Masaharu Nishimura, Yoshinosuke Fukuchi, Atsushi Nagai, Michiaki Mishima, Keishi Kubo

Journal:

Respiratory Medicine

Year:

2010

Language:

english

File:

PDF, 495 KB

english, 2010

34

Defective antigen-induced lymphocyte proliferation in the X-linked hyper-IgM syndrome

Rohan Ameratunga, Howard M. Lederman, Kathleen E. Sullivan, Hans D. Ochs, Kuniaki Seyama, John K. French, Ross Prestidge, John Marbrook, William C. Fanslow, Jerry A. Winkelstein

Journal:

The Journal of Pediatrics

Year:

1997

Language:

english

File:

PDF, 431 KB

english, 1997

35

Enteroviral meningoencephalitis as a complication of X-linked hyper IgM syndrome

Coleen K. Cunningham, Cynthia A. Bonville, Hans D. Ochs, Kuniaki Seyama, Patricia A. John, Harley A. Rotbart, Leonard B. Weiner

Journal:

The Journal of Pediatrics

Year:

1999

Language:

english

File:

PDF, 199 KB

english, 1999

36

Unrelated umbilical cord stem cell transplantation for X-linked immunodeficiencies

Ulrike H.M. Ziegner, Hans D. Ochs, Carolyn Schanen, Stephen A. Feig, Kuniaki Seyama, Takeshi Futatani, Thomas Gross, Mary Wakim, Robert L. Roberts, David J. Rawlings, Sinisa Dovat, John K. Fraser, E.R

Journal:

The Journal of Pediatrics

Year:

2001

Language:

english

File:

PDF, 257 KB

english, 2001

37

Hypoxia induces gefitinib resistance in non-small-cell lung cancer with both mutant and wild-type epidermal growth factor receptors

Kunihiko Minakata, Fumiyuki Takahashi, Takeshi Nara, Muneaki Hashimoto, Ken Tajima, Akiko Murakami, Fariz Nurwidya, Suzu Yae, Fumiaki Koizumi, Hiroyuki Moriyama, Kuniaki Seyama, Kazuto Nishio, Kazuhis

Journal:

Year:

2012

Language:

english

File:

PDF, 639 KB

english, 2012

38

Lymphangioleiomyoma Cells and Lymphatic Endothelial Cells: Expression of VEGFR-3 in Lymphangioleiomyoma Cell Clusters

Kuniaki Seyama, Keiko Mitani, Toshio Kumasaka, Shiv K. Gupta, Saji Oommen, Gang Liu, Jay H. Ryu, Nicholas E. Vlahakis

Journal:

The American Journal of Pathology

Year:

2010

Language:

english

File:

PDF, 57 KB

english, 2010

39

Genomic structure and PCR-SSCP analysis of the human CD40 ligand gene: Its application to prenatal screening for X-linked hyper-IgM syndrome

Kuniaki Seyama,Shiro Kira,Kazumi Ishidoh,Sanae Souma…

Journal:

Year:

1996

Language:

english

File:

PDF, 916 KB

english, 1996

40

The discovery of a Persian family with a form of Birt–Hogg–Dubé syndrome lacking the typical cutaneous stigmata of the syndrome

Ali Babaei Jandaghi, Saeid Daliri, Mika Kikkawa, Mojdeh Khaledi, Narjes Soleimanifar, Ahmad Alizadeh, Mahmoud Habibzadeh, Mohammad Taghi Haghi-Ashtiani, Kuniaki Seyama, Nima Rezaei

Journal:

Clinical Imaging

Year:

2013

Language:

english

File:

PDF, 844 KB

english, 2013

41

Pulmonary Erdheim-Chester disease: A response to predonisolone

Kumi Yoneda Nagahama, Takuo Hayashi, Tetsutaro Nagaoka, Ryota Kanemaru, Shinsaku Togo, Toshio Kumasaka, Toshimasa Uekusa, Kuniaki Seyama, Kazuhisa Takahashi

Journal:

Respiratory Medicine CME

Year:

2011

Language:

english

File:

PDF, 902 KB

english, 2011

42

Quantitative CT analysis of small pulmonary vessels in lymphangioleiomyomatosis

Katsutoshi Ando, Kazunori Tobino, Masatoshi Kurihara, Hideyuki Kataoka, Tokuhide Doi, Yoshito Hoshika, Kazuhisa Takahashi, Kuniaki Seyama

Journal:

European Journal of Radiology

Year:

2012

Language:

english

File:

PDF, 542 KB

english, 2012

43

Uterine angiosarcoma associated with lymphangioleiomyomatosis in a patient with tuberous sclerosis complex: an autopsy case report with immunohistochemical and genetic analysis

Takuo Hayashi, Kengo Koike, Toshio Kumasaka, Tsuyoshi Saito, Keiko Mitani, Yasuhisa Terao, Daiki Ogishima, Takashi Yao, Satoru Takeda, Kazuhisa Takahashi, Kuniaki Seyama

Journal:

Human Pathology

Year:

2012

Language:

english

File:

PDF, 2.55 MB

english, 2012

44

Senescence Marker Protein-30 Protects Mice Lungs from Oxidative Stress, Aging, and Smoking

Sato, Tadashi, Seyama, Kuniaki, Sato, Yasunori, Mori, Hiroaki, Souma, Sanae, Akiyoshi, Taeko, Kodama, Yuzo, Mori, Takanori, Goto, Sataro, Takahashi, Kazuhisa, Fukuchi, Yoshinosuke, Maruyama, Naoki, Is

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2006

Language:

english

File:

PDF, 331 KB

english, 2006

45

Oncostatin M Modulates Fibroblast Function via Signal Transducers and Activators of Transcription Proteins–3

Nagahama, Kumi Yoneda, Togo, Shinsaku, Holz, Olaf, Magnussen, Helgo, Liu, Xiangde, Seyama, Kuniaki, Takahashi, Kazuhisa, Rennard, Stephen I.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2013

Language:

english

File:

PDF, 6.07 MB

english, 2013

46

Clinical Efficacy and Safety of Transdermal Tulobuterol in the Treatment of Stable COPD: An Open-Label Comparison with Inhaled Salmeterol

Yoshinosuke Fukuchi, Atsushi Nagai, Kuniaki Seyama…

Journal:

Treatments in Respiratory Medicine

Year:

2005

Language:

english

File:

PDF, 127 KB

english, 2005

47

What׳s the role of sirolimus on the treatment of lymphangioleiomyomatosis (LAM)?: Merely tuning up of LAM-associated dysfunctional lymphatic vessels rather than cytoreduction?

Suina, Kentaro, Hayashi, Takuo, Mitani, Keiko, Suzuki, Kenji, Takahashi, Kazuhisa, Seyama, Kuniaki

Journal:

Respiratory Investigation

Year:

2014

Language:

english

File:

PDF, 995 KB

english, 2014

48

Prevalence and clinical features of lymphedema in patients with lymphangioleiomyomatosis

Hoshika, Yoshito, Hamamoto, Takako, Sato, Kayoko, Eto, Hikaru, Kuriyama, Sachiko, Yoshimi, Kaku, Iwakami, Shin-ichiro, Takahashi, Kazuhisa, Seyama, Kuniaki

Journal:

Respiratory Medicine

Year:

2013

Language:

english

File:

PDF, 934 KB

english, 2013

49

Screening of point mutations on p53 gene in tissues from primary lung cancer using single-strand conformation polymorphisms analysis

Matsuda, Kunihiro, Takahashi, Hideki, Seyama, Kuniaki, Ohwada, Akihiko, Nukiwa, Toshihiro, Kira, Shiro

Journal:

Year:

1991

Language:

english

File:

PDF, 128 KB

english, 1991

50

The efficacy and safety of low-dose sirolimus for treatment of lymphangioleiomyomatosis

Ando, Katsutoshi, Kurihara, Masatoshi, Kataoka, Hideyuki, Ueyama, Masako, Togo, Shinsaku, Sato, Teruhiko, Doi, Tokuhide, Iwakami, Shin-ichiro, Takahashi, Kazuhisa, Seyama, Kuniaki, Mikami, Masashi

Journal:

Respiratory Investigation

Year:

2013

Language:

english

File:

PDF, 1.19 MB

english, 2013